Cancer and Chemotherapy Resources and a brief guide to NCI Resources

elena petelos

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Επειδή την προηγούμενη μόλις βδομάδα είδα (έκανα ΒΤ) το Tx/tx  και το Dx/dx να έχουν μείνει Tx/tx  και Dx/dx στα Ελληνικά:

General Abbreviations & Acronyms
Item Description

ACS: American Cancer Society   (800) 227-2345
ANC: Absolute Neutrophil Count
ASAP: as soon as possible
ASCO: American Society of Clinical Oncology
BTW: by the way
cGy: centi-Gray, unit of radiation
CR: Complete Remission or Complete Response
CYA: cover your ass (letter) 
DNA: Deoxyribonucleic acid
dx: diagnosed  
EBV: Epstein Barr Virus 
ESR: Erythrocyte Sedimentation Rate 
FDA: Food and Drug Administration 
FISH: Fluorescence in situ Hybridization 
FMLA: Family Medical Leave Act 
FYI: for your information
<g>: grin

GVHD: Graft vs Host Disease
Gy: Gray, unit of radiation
HD: Hodgkin's Disease
Hem: Hematologist
hx: history
IBMTR: International Bone Marrow Transplantation Registry
IFN: Interferon
Ig: Immunoglobulin 
IMO: in my opinion
IP: Infusion Pump
JCO: Journal of Clinical Oncology
LD: lymphocyte depletion
LOL: laughing out loud or lots of laughs 
LP: lymphocyte predominance
LTS: long term survivor 
LyP: Lymphomatoid Papulosis
MC: mixed cellularity 
mg: Milli Gram
MUD: Matched Unrelated Donor
&nbsp;: non breakable space (HTML code, should not be found in mail)
NCI: National Cancer Institute   1 (800) 4-cancer
NEJM: New England Journal of Medicine
NHL: non hodgkin's lymphoma
NMDP: National Marrow Donor Program   1 (800) 526-7809
NS: nodular sclerosis
Onc: Oncologist
OPSI: overwhelming post-splenectomy infection
PBL: Peripheral Blood Lymphocytes
PBSCR: Peripheral Blood Stem Cell Rescue
PCR: Polymerase Chain Reaction
PDQ: Physician's Data Query
PFT: pulmonary function test
PFS: Progression-Free Survival
p.o.: Per os (by mouth)
PR: Partial Remission
rad: radiation
RBC: Red Blood Cell, or Red Blood Count
RFM: read the f*cking manual
RNA: RiboNucleic Acid
ROFLOL: rolling on the floor laughing out loud
RS: Reed - Sternberg (cells)
RTFM: read the f*cking manual
S.O.: Significant Other
SVT: Super Ventricular Tachycardia
tx: treatment
URL: Universal Resource Locator (used on the World Wide Web)
VUI: very useful information
WBC: White Blood Count or White Blood Cells
wks: weeks
WWW: World Wide Web

Chemotherapy Drug Abbreviations & Acronyms
Item Drugs
ABVD: Adriamycin (= Doxorubicin = Hydroxyl Daunorubcin)
         Bleomycin (= Blenoxane = Bleomycin Sulfate)
         Dacarbazine (= DTIC)

AraC: Arabinosylcytosine (= 1-ί-D-Arabinofuranosylcytosine = Cytarabine = Cytosine       

BCNU: Carmustine (= Bischloroethyl nitrosourea)

BEAC: BCNU (= Carmustine)
         AraC (= Cytarabine arabinoside = Cytosine)

ChlVPP: Chlorambucil
           Prednisone (UK: Prednisolone)

COPP: Cyclophosphamide
          Oncovin (= Vincristine)
          Procarbazine (= Matulane)

CVPP: Cyclophosphamide
Dexa-BEAM: Dexamethasone

DTIC: dimethyl-triazeno-imidazole-carboxamide

EPOCH: Etoposide
           Oncovin (= Vincristine)
ESHAP: Etoposide [240 mg/m2]
          Solu-Medrol [500 mg/d] (= Methylprednisone)
          High-dose Ara-C [2 g/m2] (= Cytarabine)
          Platinum [100 mg/m2] (= Cisplatin)
(ESHAP is a salvage chemo regimen) 

G-CSF: Granulocyte Colony-Stimulating Factor (Amgen)

GM-CSF: Granulocyte-Macrophage Colony Stimulating Factor

Gemzar: Gemcitabine HCl (Eli Lilly NDA 20-509)

IFX: Ifosfamide

Mesna: Mercaptoethane sulfonate

MGDF: Megakaryocyte Growth and Development Factor
          (platelet growth factor in clinical trial)

MINE: Mesna [4 g/m2]
         Ifosfamide [4 g/m2]
         Novantrone [8 mg/m2] (= Mitoxantrone)
         Etoposide [195 mg/m2]
        (often used as MINE-ESHAP)

Mini-BEAM: BCNU (= Carmustine)
               Etoposide (= VP-16)
               AraC (= Cytarabine)
               Melphalan (= Alkeran)

MOPP: Mustine (= Nitrogen Mustard = Mustargen = Mechlorethamine)
          Oncovin (= Vincristine)
          Procarbazine (= Matulane)

MPV: Mechlorethamine

PABLOE: Prednisone
            Adriamycin (= Doxorubicin = Hydroxyl Daunorubcin)
            Oncovin (= Vincristine)

VBM: Vinblastine
        (under clinical trial at Stanford)


VEPE: Vincristine

VNR: Vinorelbine

VP-16:  Etoposide (= Epipodophyllotoxin)

Test & Treatment Abbreviations & Acronyms

Item Description
ABMT: Autologous Bone Marrow Transplant
BMB: bone marrow biopsy
BMT: bone marrow transplant 
CHEMO: Chemotherapy 
CT: Computed Tomography (scan)
FDG: 2-deoxy-2-(18F)fluoro-deoxyglucose
HDC: High Dose Chemotherapy
MRI: Magnetic Resonance Imaging
MUD: matched unrelated donor (transplant)
PET Positron Emission Tomography
PFT: Pulmonary Function Test
SBMT: Syngeneic Bone Marrow Transplant (identical twin's marrow) 
SCT: stem cell transplant
SPECT: Single-Photon Emission Computed Tomography
SRS: Somatostatin Resceptor Scintigraphy ("Octreoscan")

η καλύτερη πηγή πληροφόρησης για σχετικά κείμενα είναι φυσικά το NCI:
Πιο συγκεκριμένα (μια και πρόσφατα άλλαξαν κάποια πράγματα):

Best Bets for Dictionary and Terminology Resources

Dictionary of Cancer Terms
A dictionary of more than 4,000 cancer-related terms. This resource is updated monthly; new terms are reviewed by a multidisciplinary panel of reviewers, and approximately 30 terms are added each month.

NCI Drug Dictionary
A dictionary that contains technical definitions, alternate names, and links to related information for approximately 700 agents that are being used in the treatment of patients with cancer or cancer-related conditions.

Terminology Resources: NCI Thesaurus, Enterprise Vocabulary Services (EVS), and Dictionaries
NCI's reference terminology and related vocabulary resources to help researchers, clinicians, and administrators identify types of cancer, treatments, and other cancer-related topics.

Common Toxicity Criteria and Common Terminology Criteria for Adverse Events
Standard terminology used to name and to describe the severity (grade) of adverse events that occur in the treatment of cancer.

Cancer Data Standards Repository for Common Data Elements
A repository of terms that medical providers may use to collect patient information for clinical trials or for cancer care. NCI hopes to facilitate uniform standards for cancer clinical trials and patient care by assembling and maintaining this information on-line for all interested caregivers.

Clinical Trials Resource: Glossary and Acronyms
An alphabetical listing of selected terms commonly used in cancer prevention clinical trials.

Glossary of Statistical Terms
Defines common statistical terms, NCI terminology, and the five key statistical measures of cancer: incidence, mortality, survival, prevalence, and lifetime risk. NCI monitors these cancer statistics to assess progress and to identify population subgroups and geographic areas in which cancer control efforts need to be concentrated.

NCI Consumers' Cancer Dictionary for Peer Review
Provides concise definitions of technical terms frequently used in applications for NCI-sponsored investigator-initiated research.

IBMFS - glossary of terms 
It is very difficult to present information related to studies in cancer genetics without using many words that are unfamiliar to most folks. The following is a list of definitions of some of the technical terms that are used on this Website. We hope that this information will make it easier to understand the material that we are presenting. 
Breast Imaging Study Glossary of Terms
A gene on chromosome 17 that normally helps to suppress cell growth. A person who inherits an altered ("mutated") version of the BRCA1 gene has a higher risk of getting breast and ovarian cancer. 
Glossary - Proteomics - National Cancer Institute
Active Site The region of an enzyme where a chemical reaction catalyzed by the enzyme occurs. Mutations that affect the active site of an enzyme can abolish or alter the function of the protein. Altered enzyme activity or function is a common theme in cancer. See also Enzyme, Protease. 
Glossary of Terms, NCI Legislative Update for National Cancer Advisory Board Congressional Activities for the 107th Congress - March 25, 2002
Concurrent Resolutions (H. Con. Res. or S. Con. Res.) - Measures concerning the affairs of both houses, such as an expression of mutual sentiment of budget limits, the creation of a joint committee, agreement on a joint session or joint meeting, or agreement on the time if final adjournment of the whole Congress. A concurrent resolution must be adopted by both houses, but is not sent to the President for his signature and therefore does not have the force of law. 

Και λοιπά! :-)))
« Last Edit: 16 Jun, 2006, 18:36:01 by elena petelos »


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